PALB2 & CHEK2 genes
Please find an overview and risks of the PALB2 and CHEK2 genes.
PALB2
- Breast Cancer lifetime risk: 30-80% (varies on family history)
- Ovarian Cancer lifetime risk: 5%
- Contralateral Breast Cancer lifetime risk: varies on family history
CHEK2 (1100delC variant only)
- Breast Cancer lifetime risk: 37%
- Ovarian Cancer lifetime risk: Not significantly increased
- Possible increased risks for thyroid and Prostate Cancer Currently outside test directory and may be removed.
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Gene Information
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